Hydrazine → 6-chloro-1H-indazol-3-amine

HRID 1283706Notes

Reaction equation

HRID 1283706 reaction equation
[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[C:4](I)[CH:3]=1.[NH2:11][NH2:12]>C(O)C>[NH2:7][C:6]1[C:5]2[C:4](=[CH:3][C:2]([Cl:1])=[CH:9][CH:8]=2)[NH:12][N:11]=1

Participants

4

Reactant 2

HCID 9321HydrazineHCID 215161654-Chloro-2-iodobenzonitrile

Product 1

HCID 856286-chloro-1H-indazol-3-amine

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 10.0 g. of 4-chloro-2-iodobenzonitrile, 5 ml. of 95% hydrazine and 50 ml. of ethanol is allowed to stand for 24 hours at 50° C. Working up as in Example 1 gives 3-amino-6-chloroindazole.

Workup

  1. additionA mixture of 10.0 g

Sources & evidence

ORD record
ord-4432c155764540d0b200184d05577cd0
Source dataset
uspto-grants-1976_08
Patent number
USRE028939

Reaction notes

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