Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 2-Amino-5-bromobenzonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Aniline | HCID 6115 | — |
| 반응물 | 5-Bromo-2-nitrobenzonitrile | HCID 319489 | — |
| 반응물 | 5-Bromo-2-nitroaniline | HCID 5314766 | — |
| 반응물 | Sodium Nitrite | HCID 23668193 | — |
| 생성물 | 2-Amino-5-bromobenzonitrile | HCID 429740 | — |
반응 단계
5-bromo-2-nitroaniline is converted into 5-bromo-2-nitrobenzonitrile by treating the aniline derivative with sodium nitrite and hydrochloric acid and reacting the resulting diazonium salt with cuprous cyanide as in Example 2. The nitro group is reduced with stannous chloride and hydrochloric acid to give 4-bromo-2-cyanoaniline.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | USRE028939 |
| 출처 데이터셋 | uspto-grants-1976_08 |
| ORD ID | ord-402c2e5e38754d98aebd03196adc02af |
| 출처 메모 | uspto-grants-1976_08 |