HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Water → N-Methyl-5-(trifluoromethyl)-1H-indazol-3-amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Water | HCID 962 | — |
| Edukt | Aluminium lithium hydride | HCID 21226445 | — |
| Edukt | N-(5-(trifluoromethyl)-1H-indazol-3-yl)formamide | HCID 21409159 | — |
| Lösungsmittel | Diethyl Ether | HCID 3283 | — |
| Produkt | N-Methyl-5-(trifluoromethyl)-1H-indazol-3-amine | HCID 21991113 | — |
Reaktionsschritte
An ether solution of 3-formylamino-5-trifluoromethylindazole is added to 2.0 g. of lithium aluminum hydride in ether. The resulting mixture is refluxed for 16 hours. Ether is added, followed by water. The mixture is filtered and the filtrate is concentrated. The residue is recrystallized from benzene to give 3-methylamino-5-trifluoromethylindazole.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | USRE028939 |
| Quelldatensatz | uspto-grants-1976_08 |
| ORD ID | ord-941196174a0344d18f272d05431f9df5 |
| Quellennotiz | uspto-grants-1976_08 |