HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine → N,N-Diethyl-5-(trifluoromethyl)-1H-indazol-3-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine | HCID 9321 | — |
| Reactant | 2-Bromo-N,N-diethyl-5-(trifluoromethyl)benzene-1-carboximidamide | HCID 21516167 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | N,N-Diethyl-5-(trifluoromethyl)-1H-indazol-3-amine | HCID 21516162 | — |
Reaction Steps
A mixture of 5.0 g. of N,N-diethyl-2-bromo-5-trifluoromethylbenzamidine and 2.0 ml. of 95% hydrazine are refluxed in butanol for 12 hours. Evaporating the solution, treating the residue with ether and filtering gives 3-diethylamino-5-trifluoromethylindazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | USRE028939 |
| Source dataset | uspto-grants-1976_08 |
| ORD ID | ord-d379bb1eddcd410fbd705f9b721a60d9 |
| Source note | uspto-grants-1976_08 |