Aluminium lithium hydride → HCID 21516461, compound

Participants

Reaction Steps

An ice-cold suspension of 1.5 grams (0.040 mole) of lithium aluminum hydride in 35 ml. of dry tetrahydrofuran is treated dropwise over a period of about 30 minutes with a solution of 10.9 grams (0.039 mole) of 3-phenethylmethylamino-2-methylindan-1-one in 80 ml of tetrahydrofuran. The mixture is stirred at 0° for 4 hours and then quenched by the addition of ethylacetate, 2N sodium hydroxide and water. The solids are filtered, an the filtrate is dried over magnesium sulfate, filtered and evaporated to yield 3-phenethylmethylamino-2-methylindan-1-ol as an oil.

Provenance & Evidence