HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acrylonitrile → HCID 86733852, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acrylonitrile | HCID 7855 | — |
| Reactant | 1,3-Dihydro-3-hydroxy-3-[(3-methoxyphenyl)methyl]-2H-indol-2-one | HCID 3155253 | — |
| Product | HCID 86733852 | HCID 86733852 | — |
Reaction Steps
Reaction of acrylonitrile with -3-(m-anisyl)-3-hydroxyindolin-2-one by a process analogous to that of Example 1 gives 1-(2-cyanoethyl)-3-(m-anisyl)-3-hydroxy-indolin- 2-one. Hydrogenation of the 1-(2-cyanoethyl)- 3-(m-anisyl) 3-hydroxy-indolin-2-one by a procedure analogous to that of Example 2 gives 1-(3-aminopropyl)- 3-(m-anisyl)-3-hydroxy-indolin-2-one. Cyclodehydration of the 1-(3-aminopropyl)-3-(m-anisyl)-3-hydroxy-indolin- 2-one by a procedure analogous to that of Example 3 gives 10-(m-anisyl)-2,3,4,10-tetrahydro-pyrimido[1,2-a] indol 10-ol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03976645 |
| Source dataset | uspto-grants-1976_08 |
| ORD ID | ord-903a99e4cb1a4006aae54864cce141b7 |
| Source note | uspto-grants-1976_08 |