Dimethylamine → HCID 21516410, compound

Participants

Reaction Steps

A solution of 10.0 g. (0.026 mol.) of 1,3-bis(2-cyano-5-trifluoromethylphenyl)triazene and 1.8 g. of sodium hydride in 750 ml. of ether is added to a solution of 4.45 g. (0.026 mol.) of 3-bromopropionyl chloride in 50 ml. of ether. The reaction mixture is stirred for 12 hours at 25°, then filtered to remove the precipitate formed during the reaction. The filtrate is cooled to -10° and dimethylamine (0.026 mol.) is added. The mixture is cooled for 12 hours, concentrated in vacuo and the residue is washed with ether-hexane and dried in vacuo to give 3-[2-(N,N-dimethylamino)propionyl]-1,3-bis(2-cyano-5-trifluoromethylphenyl)triazene hydrobromide.

Provenance & Evidence