1-N-Cbz-pyrrolidine-3-carboxylic acid → HCID 21516697, compound

HRID 1283844Notes

Reaction equation

HRID 1283844 reaction equation
[C:1]([CH:4]1[CH2:8][CH2:7][N:6](C(OCC2C=CC=CC=2)=O)[CH2:5]1)([OH:3])=[O:2].[CH2:19](OC(C1CCCN1)=O)[CH2:20][CH2:21][CH2:22][CH2:23][CH3:24]>>[CH2:19]([O:3][C:1]([CH:4]1[CH2:8][CH2:7][NH:6][CH2:5]1)=[O:2])[CH2:20][CH2:21][CH2:22][CH2:23][CH3:24]

Participants

3

Reactant 2

HCID 185384831-N-Cbz-pyrrolidine-3-carboxylic acidHCID 19991658HCID 19991658, compound

Product 1

HCID 21516697HCID 21516697, compound

Procedure

By substituting the 3-carboxy-1-phenylmethyloxycarbonylpyrrolidine obtained in Example 10 for the 2-[(hexyloxy)carbonyl]pyrrolidine in the procedure of Example 1, 3-[(hexyloxy)carbonyl]pyrrolidine is obtained.

Sources & evidence

ORD record
ord-79dbd55b27174016bebb681bfe5f1c88
Source dataset
uspto-grants-1976_08
Patent number
US03976660

Reaction notes

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