Potassium Hydroxide → (1,1'-Biphenyl)-2-ol

HRID 1283854Notes

Reaction equation

HRID 1283854 reaction equation
[CH:1]1[CH:6]=[CH:5][C:4]([C:7]2[C:12]([O-:13])=[CH:11][CH:10]=[CH:9][CH:8]=2)=[CH:3][CH:2]=1.[Na+].[OH-].[K+]>>[C:4]1([C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][C:12]=2[OH:13])[CH:3]=[CH:2][CH:1]=[CH:6][CH:5]=1

Participants

3

Reactant 2

HCID 14797Potassium HydroxideHCID 23675735Sodium 2-phenylphenate

Product 1

HCID 7017(1,1'-Biphenyl)-2-olYield 92.2%

Procedure

Starting from 7.35 g of potassium o-phenyl-phenate, obtained "in situ" by salifying 6 g of o-phenyl-phenol with KOH, and from 4.2 g of acetophenone (molar ratio = 1:1), it was possible to obtain, by operating as in Example 1, 0.5 g of benzoylacetic acid. Under the same conditions, potassium p-phenyl-phenate did not cause any sensible reaction.

Sources & evidence

ORD record
ord-72362ef23162423f9377c8dc3d74eedf
Source dataset
uspto-grants-1976_08
Patent number
US03976677

Reaction notes

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