Hydrochloric Acid → HCID 21516781, compound

Participants

Reaction Steps

A mixture of methyl [1',3'-dioxo-4'-chloro-5'-methylspiro(cyclopentane-1,2'-indan)-6'-yloxy]acetate (3.5 g., 0.0104 mole) potassium hydroxide (0.67 g., 0.012 mole) and methanol (200 ml.) is refluxed for 1/2 hour, diluted with water (800 ml.) and acidified with hydrochloric acid affording 3.1 g. of [1',3'-dioxo-4'-chloro-5'-methylspiro(cyclopentane-1,2'-indan)-6'-ylox]acetic acid which melts at 204°-4°C. after recrystallization from acetic acid-water.

Provenance & Evidence