HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → 2-Chloro-3,4-dihydroxybenzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Boron tribromide | HCID 25134 | — |
| Reactant | Chloroisovaniline | HCID 603956 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-Chloro-3,4-dihydroxybenzaldehyde | HCID 598814 | — |
Reaction Steps
To a stirred solution of 25 g. (0.134 m.) of 2-chloroisovanillin in 80 ml. of methylene chloride at 0°C. is added dropwise 19 ml. (0.2 m.) of boron tribromide and the mixture is stirred at 25°C. for 3 hours. Methanol (100 ml.) is added and the solution is concentrated to give 2-chloroprotocatechualdehyde, m.p. 193°-195°C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03976695 |
| Source dataset | uspto-grants-1976_08 |
| ORD ID | ord-bf9933328a3f48abadf48c4b2bc089d5 |
| Source note | uspto-grants-1976_08 |