Isopropylamine → HCID 68141882, compound

HRID 1283897Notes

Reaction equation

HRID 1283897 reaction equation
[Cl:1][C:2]1[C:7]([CH:8]2[O:10][CH2:9]2)=[CH:6][C:5]([O:11][CH2:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[C:4]([O:19][CH2:20][C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[CH:3]=1.[CH:27]([NH2:30])([CH3:29])[CH3:28]>>[ClH:1].[Cl:1][C:2]1[C:7]([CH:8]([OH:10])[CH2:9][NH:30][CH:27]([CH3:29])[CH3:28])=[CH:6][C:5]([O:11][CH2:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[C:4]([O:19][CH2:20][C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[CH:3]=1

Participants

3

Reactant 2

HCID 6363IsopropylamineHCID 21516836HCID 21516836, compound

Product 1

HCID 68141882HCID 68141882, compound

Procedure

Following the procedures of Example 6, 6-chloro-3,4-dibenzyloxystyrene oxide is refluxed with isopropylamine to give 6-chloro-α-(isopropylaminomethyl)-3,4-dibenzyloxybenzyl alcohol hydrochloride, m.p. 154°-163°C., which is hydrogenated to yield 6-chloro-α-(isopropylaminomethyl)-3,4-dihydroxybenzyl alcohol hydrochloride, m.p. 171°-172°

Sources & evidence

ORD record
ord-641fbcf6f3b445c48b82f44bf9eda1c5
Source dataset
uspto-grants-1976_08
Patent number
US03976695

Reaction notes

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