Benzoyl Peroxide → HCID 21516828, compound

HRID 1283900Notes

Reaction equation

[Br:1]Br.[Cl:3][CH:4]([CH:13]([O:23][CH2:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)[CH2:14][O:15][CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[C:5]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)=[O:6].C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)Cl>[Br:1][C:4]([Cl:3])([CH:13]([O:23][CH2:24][C:25]1[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=1)[CH2:14][O:15][CH2:16][C:17]1[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=1)[C:5]([C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=1)=[O:6]

Participants

Conditions

Temperature: 25 °C

Procedure

A solution of bromine (16.0 g., 0.1 m.) in 100 ml. of chloroform is added dropwise to a stirred solution of 39.5 g. (0.1 m.) of 2-chloro-3,4-dibenzyloxybutyrophenone and 0.2 g. of dibenzoyl peroxide in 650 ml. of chloroform. After stirring for 30 minutes at 25°C., the reaction mixture is washed with water, aqueous saturated sodium bicarbonate and again with water. The chloroform solution is dried and concentrated in vacuo to leave a residue of α-bromo-2-chloro-3,4-dibenzyloxybutyrophenone.

Workup

washthe reaction mixture is washed with water, aqueous saturated sodium bicarbonate and again with water
dry with materialThe chloroform solution is dried
concentrationconcentrated in vacuo

Sources & evidence

ORD record: ord-a2c6f0b9e62342dd87f971be3d9f167a
Source dataset: uspto-grants-1976_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03976695

Reaction notes

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