Acetonitrile → HCID 21516837, compound

Participants

Reaction Steps

A solution of 9.5 g. (0.02 m.) of the above α-bromobutyrophenone and 6.0 g. (0.04 m.) of N-benzylisopropylamine in 60 ml. of acetonitrile is stirred at 25°C. for 1 hour. The mixture is diluted with ether and filtered to remove N-benzylisopropylamine hydrobromide. The filtrate is treated with ethereal hydrogen chloride to give α-(N-benzylisopropylamino)-2-chloro-3,4-dibenzyloxybutyrophenone hydrochloride.

Provenance & Evidence