1-(4-Chlorobutyl)-1-methyl-6-methoxy-2-tetralone → 6,7,8,9,10,11-Hexahydro-2-Methoxy-5Methyl-5,10-Methano-5H-Benzocyclononen-12-One

HRID 1283911Notes

Reaction equation

HRID 1283911 reaction equation
COC1C=CC2CC3C(=O)C(C)(C=2C=1)CCCC3.Cl[CH2:20][CH2:21][CH2:22][CH2:23][C:24]1([CH3:37])[C:33]2[C:28](=[CH:29][C:30]([O:34][CH3:35])=[CH:31][CH:32]=2)[CH2:27][CH2:26][C:25]1=[O:36]>>[CH3:35][O:34][C:30]1[CH:31]=[CH:32][C:33]2[C:24]3([CH3:37])[C:25](=[O:36])[CH:26]([CH2:20][CH2:21][CH2:22][CH2:23]3)[CH2:27][C:28]=2[CH:29]=1

Participants

3

Reactant 2

HCID 214100831-(4-Chlorobutyl)-1-methyl-6-methoxy-2-tetraloneHCID 214101236,7,8,9,10,11-hexahydro-3-methoxy-5-methyl-5,10-methano-5H-benzocyclononen 12-one

Product 1

HCID 214101276,7,8,9,10,11-Hexahydro-2-Methoxy-5Methyl-5,10-Methano-5H-Benzocyclononen-12-One

Procedure

Using a procedure analogous to that described in Example X for the preparation of 6,7,8,9,10,11-hexahydro-3-methoxy-5-methyl-5,10-methano-5H-benzocyclononen-12-one, there is obtained from 30.5 g. of 1-(4-chlorobutyl)-1-methyl-6-methoxy-2-tetralone 15 g. of the title product, b.p. 140° to 145° C. (0.5 mm.).

Workup

  1. customthere is obtained from 30.5 g

Sources & evidence

ORD record
ord-678508b676124a2e81f107c1ac1e380b
Source dataset
uspto-grants-1976_08
Patent number
US03976693

Reaction notes

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