1-(4-Chlorobutyl)-1-Ethyl-7-Methoxy-2-Tetralone → 5-Ethyl-6,7,8,9,10,11-Hexahydro-3-Methoxy-5,10-Methano-5H-Benzocyclononen-12-One

HRID 1283913Notes

Reaction equation

HRID 1283913 reaction equation
COC1C=CC2CC3C(=O)C(C)(C=2C=1)CCCC3.Cl[CH2:20][CH2:21][CH2:22][CH2:23][C:24]1([CH2:37][CH3:38])[C:33]2[C:28](=[CH:29][CH:30]=[C:31]([O:34][CH3:35])[CH:32]=2)[CH2:27][CH2:26][C:25]1=[O:36]>>[CH2:37]([C:24]12[C:25](=[O:36])[CH:26]([CH2:27][C:28]3[CH:29]=[CH:30][C:31]([O:34][CH3:35])=[CH:32][C:33]=31)[CH2:20][CH2:21][CH2:22][CH2:23]2)[CH3:38]

Participants

3

Reactant 2

HCID 214101171-(4-Chlorobutyl)-1-Ethyl-7-Methoxy-2-TetraloneHCID 214101236,7,8,9,10,11-hexahydro-3-methoxy-5-methyl-5,10-methano-5H-benzocyclononen 12-one

Product 1

HCID 214100725-Ethyl-6,7,8,9,10,11-Hexahydro-3-Methoxy-5,10-Methano-5H-Benzocyclononen-12-One

Procedure

Using a procedure analogous to that described in Example X for the preparation of 6,7,8,9,10,11-hexahydro-3-methoxy-5-methyl-5,10-methano-5H-benzocyclononen-12-one there is obtained from 37.4 g. of 1-(4-chlorobutyl)-1-ethyl-7-methoxy-2-tetralone, 22.2 g. of the title product, b.p. 138° to 142° C. (0.35 mm.).

Workup

  1. customthere is obtained from 37.4 g

Sources & evidence

ORD record
ord-4b8c4d29318a4230abd9765d88bd17d7
Source dataset
uspto-grants-1976_08
Patent number
US03976693

Reaction notes

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