Acetic Anhydride → HCID 21517129, compound

Participants

Reaction Steps

A stirred suspension of N-n-butyl-3,5-dinitroaniline (5.5 g.) in acetic anhydride (20 ml.) was treated with a few drops of concentrated sulphuric acid and then heated on the steam bath for 3 hours. The cooled reaction mixture was added to ice-water (400 ml.) and the product was extracted with ethyl acetate (3 × 100 ml.). The combined organic extract was washed with 2N aqueous sodium bicarbonate solution, dried with anhydrous magnesium sulphate, and the solvent removed in vacuo, to give 3',5'-dinitro-N-n-butylacetanilide (2.8 g.), in the form of an amber syrup, ν1670 cm-1.

Provenance & Evidence