Acetic Anhydride → HCID 21517131, compound

HRID 1283966Notes

Reaction equation

HRID 1283966 reaction equation
C(O[C:5](=[O:7])C)(=O)C.[CH3:8][NH:9][C:10]1[CH:15]=[C:14]([N+:16]([O-:18])=[O:17])[CH:13]=[C:12]([N+:19]([O-:21])=[O:20])[CH:11]=1>C(O)=O>[N+:16]([C:14]1[CH:15]=[C:10]([CH:11]=[C:12]([N+:19]([O-:21])=[O:20])[CH:13]=1)[N:9]([CH3:8])[CH:5]=[O:7])([O-:18])=[O:17]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 3930462N-methyl-3,5-dinitroaniline

Product 1

HCID 21517131HCID 21517131, compound

Reagents, catalysts & solvents 1

HCID 284Formic AcidSolvent

Procedure

A mixture of formic acid (10 ml.) and acetic anhydride (5 ml.) was stirred at room temperature for 30 minutes. N-methyl-3,5-dinitroaniline (5.0 g.) was then added and the reaction mixture was heated on a steam bath for 10 minutes. The mixture was allowed to cool to room temperature during 40 minutes, then poured into ice-water and the precipitate was filtered off. Recrystallisation from methanol gave 3',5'-dinitro-N-methylformanilide (2.2 g.), m.p. 93°-94°C.

Workup

  1. temperaturethe reaction mixture was heated on a steam bath for 10 minutes
  2. temperatureto cool to room temperature during 40 minutes
  3. filtrationthe precipitate was filtered off
  4. customRecrystallisation from methanol

Sources & evidence

ORD record
ord-99f101a087ec4fe580101d6b1ca262a1
Source dataset
uspto-grants-1976_08
Patent number
US03976786

Reaction notes

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