HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 68148114, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | (αS)-α-Amino-1,4-cyclohexadiene-1-propanoic acid | HCID 441444 | — |
| Product | HCID 68148114 | HCID 68148114 | — |
Reaction Steps
Thionyl chloride (15 ml.) is added to methanol (150 ml.) while stirring in a dry ice bath. The mixture is allowed to come to room temperature and 2,5-dihydro-L-phenylalanine (5.0 g.) is added. After refluxing for 30 minutes, the solvent is removed in vacuo and the residue is crystallized from ether and then recrystallized from acetonitrile. Yield: 4.95 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03978034 |
| Source dataset | uspto-grants-1976_08 |
| ORD ID | ord-10e2cd2170d449a9a2d77d3f92ca3ac9 |
| Source note | uspto-grants-1976_08 |