Ethyl isothiocyanate → HCID 21515289, compound

HRID 1284018Notes

Reaction equation

HRID 1284018 reaction equation
C1(C2(C#N)CCC(N3CCCC3)=CC2)C=CC=CC=1.C(N=C=S)C.[C:25]1([C:31]2([C:47]#[N:48])[CH2:36][CH2:35][C:34]([N:37]3[CH2:41][CH2:40][CH2:39][CH2:38]3)=[C:33]([C:42](=[S:46])[NH:43][CH2:44]C)[CH2:32]2)[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>>[C:25]1([C:31]2([C:47]#[N:48])[CH2:36][CH2:35][C:34]([N:37]3[CH2:41][CH2:40][CH2:39][CH2:38]3)=[C:33]([C:42](=[S:46])[NH:43][CH3:44])[CH2:32]2)[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=1

Participants

4

Reactant 3

HCID 10966Ethyl isothiocyanateHCID 13433237HCID 13433237, compoundHCID 53728394HCID 53728394, compound

Product 1

HCID 21515289HCID 21515289, compound

Procedure

Using the procedure of step B at example 10 and starting from 126.4 g 4-phenyl 4-cyano 1-pyrrolidino cyclohex-1 ene and 40 g ethyl isothiocyanate, 107.25 g of 4-phenyl 4-cyano 2-ethylthiocarbamoyl 1-pyrrolidino cyclohex-1 ene are obtained after the usual purifications.

Workup

  1. customare obtained after the usual purifications

Sources & evidence

ORD record
ord-e02fd9a1287c4eeca59aa1b8c539e96e
Source dataset
uspto-grants-1976_08
Patent number
US03978044

Reaction notes

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