反应详情

Alternatively the title compound is prepared as follows. A suspension of 5-ethoxy-1,3-dihydropyrrolo[4,3,2-de]isoquinoline (9.0 g) in dry ethanol (140 ml) is treated with acetylhydrazine (5.0 g). The mixture is heated at reflux for 2 days. Ethanol is partially removed by distillation and ether-hexane added. The solid is collected from methanol to give the title compound.

1. customAlternatively the title compound is prepared
2. temperatureThe mixture is heated
3. temperatureat reflux for 2 days
4. customEthanol is partially removed by distillation and ether-hexane
5. additionadded
6. customThe solid is collected from methanol