Water → HCID 21515664, compound

Participants

Reaction Steps

To a flask equipped with a stirrer and Dean-Stark water separator are charged 53g. of benzoin, 51g. of 3,4-methylenedioxyaniline, 2.5g. of p-toluenesulfonic acid and 300 ml. of xylene. The mixture is stirred and refluxed for 10 hours. After cooling to room temperature 1500 ml of chloroform are added and the organic layer is washed two times with 150 ml. of 10%, sulfuric acid. The organic layer is treated with charcoal, filtered and concentrated in vacuo to ca. 500 ml. On standing there is obtained 2,3-diphenyl- 5,6-methylenedioxyindole, m.p. 187°-188°C.

Provenance & Evidence