反应详情

温度

132.5 °C

A mixture of 66 g of ethyl ortho-acetate, 25 g of cyclohexylethynylcarbinol and 2.5 g of propionic acid was agitated at 130 to 135°C. for 8 hours while distilling off ethanol. The resulting liquid mixture was directly subjected to distillation under reduced pressure and a fraction boiling at 107° to 108°C. under 5 mm Hg was collected. Ethyl 5-cyclohexyl-3,4-pentadienoate was obtained in a yield of 93%.

1. distillationwhile distilling off ethanol
2. distillationThe resulting liquid mixture was directly subjected to distillation under reduced pressure
3. customa fraction boiling at 107° to 108°C. under 5 mm Hg was collected