反应详情

In the same manner as in the preceeding Examples, 32.4 g of ethyl ortho-acetate, 22 g of dehydronerolidol and 1.5 g of propionic acid were reacted at 135 to 140°C. for 6 hours and the resulting reaction mixture was subjected to distillation under reduced pressure. Ethyl 5,9,13-trimethyl-3,4,8,12-pentadecatetraenoate was obtained in a yield of 96% from a fraction boiling at 144 to 146°C. under 0.025 mm Hg.

1. customwere reacted at 135 to 140°C. for 6 hours
2. customthe resulting reaction mixture
3. distillationwas subjected to distillation under reduced pressure