HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → 1-Cyclopropyl-3-(methylamino)propan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 1-Cyclopropyl-3-(dimethylamino)propan-1-one | HCID 231985 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 1-Cyclopropyl-3-(methylamino)propan-1-one | HCID 21488080 | — |
Reaction Steps
A solution of 42.5 g. (0.3 mole) of 1-cyclopropyl-3-dimethylamino-1-propanone in 200 ml. of benzene was refluxed while methylamine was bubbled through the solution for 8 hours. The nuclear magnetic resonance spectrum indicated a 90% conversion to 1-cyclopropyl-3-methylamino-1-propanone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03978130 |
| Source dataset | uspto-grants-1976_08 |
| ORD ID | ord-9db31fdec14b4c8f9fc3a1146c4ac63c |
| Source note | uspto-grants-1976_08 |