Acrylonitrile → HCID 21516058, compound

Participants

Reaction Steps

Treat 1.3 g of 2-aminomethyl-5-chloro-3-(2-fluorophenyl)indole with 8 ml of acrylonitrile and reflux for 16 hours. Concentrate to a residue and dissolve the residue in alcohol, e.g. ethanol. Add an ethanolic solution of hydrogen chloride, collect and dry the solid which precipitates out; the title compound melts at 212- 213°C.

Provenance & Evidence