3,6-Dichloro-N-(propan-2-yl)pyridazin-4-amine → 6-Chloro-3-hydrazinyl-N-(propan-2-yl)pyridazin-4-amine
Reaction equation
Cl[C:2]1[N:3]=[N:4][C:5]([Cl:12])=[CH:6][C:7]=1[NH:8][CH:9]([CH3:11])[CH3:10].ClC1[N:15]=[N:16]C(Cl)=CC=1NCC>>[CH:9]([NH:8][C:7]1[CH:6]=[C:5]([Cl:12])[N:4]=[N:3][C:2]=1[NH:15][NH2:16])([CH3:11])[CH3:10]Participants
3
Procedure
When 3,6-dichloro-4-isopropylamino pyridazine is substituted for 3,6-dichloro-4-ethylamino pyridazine in the above process, 4-isopropylamino-6-chloro-3-hydrazino pyridazine (m.p. 132° to 135°C) is obtained.
Sources & evidence
- ORD record
- ord-1d02b2846bfd41b29b973d651414099a
- Source dataset
- uspto-grants-1976_08
- Patent number
- US03978057
Reaction notes
Loading…