Hydrazine → 4-(2-Hydroxyethylamino)-6-chloro-3-hydrazino pyridazine

HRID 1284325Notes

Reaction equation

HRID 1284325 reaction equation
Cl[C:2]1[N:3]=[N:4][C:5]([Cl:12])=[CH:6][C:7]=1[NH:8][CH2:9][CH2:10][OH:11].[NH2:13][NH2:14]>O>[OH:11][CH2:10][CH2:9][NH:8][C:7]1[CH:6]=[C:5]([Cl:12])[N:4]=[N:3][C:2]=1[NH:13][NH2:14]

Participants

4

Reactant 2

HCID 9321HydrazineHCID 215154302-((3,6-Dichloropyridazin-4-yl)amino)ethan-1-ol

Product 1

HCID 215154214-(2-Hydroxyethylamino)-6-chloro-3-hydrazino pyridazine

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To 40 g of 3,6-dichloro-4-(2-hydroxyethylamino)pyridazine is added slowly with stirring 430 g of 97% hydrazine. The mixture is stirred for 20 hours and cooled. Water is added, and the precipitate, 4-(2-hydroxyethylamino)-6-chloro-3-hydrazino pyridazine (m.p. 168° to 172°C.), is collected by filtration

Workup

  1. temperaturecooled
  2. filtrationthe precipitate, 4-(2-hydroxyethylamino)-6-chloro-3-hydrazino pyridazine (m.p. 168° to 172°C.), is collected by filtration

Sources & evidence

ORD record
ord-92f2108a6f5d401fac9f2802ffa36648
Source dataset
uspto-grants-1976_08
Patent number
US03978057

Reaction notes

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