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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1284397생성일: 2026년 10월 25일

p-Toluenesulfonic acid → 6-Acetoxy-2-naphthyl-alpha-methylacetic acid

https://huagongshe.com/reaction/1284397

반응식

참여 물질

역할이름HCID투입량
반응물p-Toluenesulfonic acidHCID 6101—
반응물Acetic AnhydrideHCID 7918—
반응물DesmethylnaproxenHCID 162920—
생성물6-Acetoxy-2-naphthyl-alpha-methylacetic acidHCID 20335192—

반응 단계

A mixture of 2.2 g. of 6-hydroxy-2-naphthyl-α-methylacetic acid, 50 ml. of acetic anhydride, and 100 mg. of p-toluenesulfonic acid is stirred for four hours at 50°C. The mixture is evaporated, water is added, and the mixture is extracted with diethyl ether which is washed with water to neutrality, dried over sodium sulfate, and evaporated to yield 6-acetoxy-2-naphthyl-α-methylacetic acid.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US03978124
출처 데이터셋uspto-grants-1976_08
ORD IDord-eddee398af6f40c2b01bd074a250b43d
출처 메모uspto-grants-1976_08