HCID 178418361, compound → HCID 178512870, compound

HRID 1284415Notes

Reaction equation

HRID 1284415 reaction equation
[NH2:1][C@@H:2]([C:10]([N:12]1[CH2:30][CH2:29][CH2:28][C@H:13]1[C:14]([NH:16][C@H:17]([C:25]([OH:27])=[O:26])[CH2:18][CH2:19][CH2:20][NH:21][C:22](=[NH:24])[NH2:23])=[O:15])=[O:11])[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.I[C:32]1[CH:33]=[C:34]([CH:37]=[CH:38][CH:39]=1)[CH2:35][NH-:36].[H][H]>>[NH2:1][C@@H:2]([C:10]([N:12]1[CH2:30][CH2:29][CH2:28][C@H:13]1[C:14]([NH:16][C@H:17]([C:25]([OH:27])=[O:26])[CH2:18][CH2:19][CH2:20][NH:21][C:22](=[NH:23])[NH2:24])=[O:15])=[O:11])[CH2:3][C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=1.[CH2:35]([NH-:36])[C:34]1[CH:37]=[CH:38][CH:39]=[CH:32][CH:33]=1

Participants

3

Reactant 2

HCID 178418361HCID 178418361, compoundHCID 178512871HCID 178512871, compound

Product 1

HCID 178512870HCID 178512870, compound

Procedure

(D)Phe-Pro-Arg-3-iodo-benzylamide, 10 mg, was dehalogenated as described in Example 9, Step H, using hydrogen gas instead of tritium gas.

Sources & evidence

ORD record
ord-30aa00ec6fcc404782e739475adb25ca
Source dataset
uspto-grants-1986_01
Patent number
US04563305

Reaction notes

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