反应详情

Following the procedure of Example 1, a mixture of 4-(2-chloro-4-trifluoromethylphenoxy)-1,2-dinitrobenzene (2.0 g, 5.52 mmol) and dimethyl phenylphosphonite (1.4 g, 8.28 mmol) in 4 ml of acetonitrile is heated under reflux overnight. The crude product is purified to yield methyl P-phenyl-2-nitro-5-(2-chloro-4-trifluoromethylphenoxy)phenylphosphinate, m/s 471 (M+).

1. temperatureis heated
2. temperatureunder reflux overnight
3. customThe crude product is purified