4-Toluenesulfonyl chloride → HCID 86737659, compound

Participants

Reaction Conditions

Reaction Steps

In order to do this, 3-aminothiochromone (7.4 g) is suspended in anhydrous pyridine (25 ml), the mixture is cooled to about 10° C. and para-toluenesulphonyl chloride (8.6 g) is then added, whist stirring. After dilution with distilled water (100 ml), precipitation, filtration, washing with ethanol and drying, 3-(p-toluenesulphonylamino)-thiochromone (13 g), which melts at 212° C., is obtained.

Provenance & Evidence