HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → P-methyl-2-cyano-5-(2-chloro-4-trifluoromethyl-phenoxy)phenylphosphinic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Bromotrimethylsilane | HCID 76113 | — |
| Reactant | methyl P-methyl-2-cyano-5-(2-chloro-4-trifluoromethylphenoxy)-phenylphosphinate | HCID 54565077 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | P-methyl-2-cyano-5-(2-chloro-4-trifluoromethyl-phenoxy)phenylphosphinic acid | HCID 20251545 | — |
Reaction Steps
To a solution of methyl P-methyl-2-cyano-5-(2-chloro-4-trifluoromethylphenoxy)-phenylphosphinate (0.46 g) in 10 ml of methylene chloride is added trimethylsilyl bromide (0.75 ml) dropwise. The mixture is stirred for 2 hours, after which methanol is added. The reaction is stripped and evaporated under vacuum to give P-methyl-2-cyano-5-(2-chloro-4-trifluoromethyl-phenoxy)phenylphosphinic acid, m/s 375 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04563310 |
| Source dataset | uspto-grants-1986_01 |
| ORD ID | ord-7699aa7626af4cf09229a17a46799fc5 |
| Source note | uspto-grants-1986_01 |