HCID 13935802, compound → HCID 15600125, compound

Participants

Reaction Steps

(3S)-1-Oxo-7-nitro-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (1 g) is suspended in acetic acid (50 g), and PtO2 (50 mg) is added thereto. The mixture is subjected to catalytic reduction. The catalyst is filtered off, and the filtrate is distilled to remove the solvent, whereby (3S)-1-oxo-7-amino-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (870 mg) is obtained as an oil.

Provenance & Evidence