Sulfuric Acid → HCID 13537991, compound

Participants

Reaction Steps

A suspension of 2-oxo-3H-oxazolo[4,5-h]quinoline (1.86 g, 10.0 mmol), acetic anhydride (50 ml) and sulfuric acid (0.5 ml) was refluxed overnight. The reaction was filtered and the filtrate concentrated. Methylene chloride was added and the resulting solution was washed (3×) with water, brine; dried over MgSO4 and concentrated to a solid. The solid was crystallized from ethanol to give 1.82 g (80% yield) of product. M.P. 192°-193° C.

Provenance & Evidence