反应详情

In a dry three-neck flask equipped with a mechanical stirrer and an addition funnel was placed 110 g of pyridinium dichromate and 200 ml of dry CH2Cl2. The mixture was stirred vigorously and then 42 g of 2,2-dimethyl-3-(4-methoxyphenylmethoxy)propanol, the product of Example 5a, was added in one portion. The resulting reaction mixture was stirred for 4 hours. The black brown mixture was poured into 400 ml ethyl ether and the mixture was filtered through a dry silica gel column to obtain a colorless solution. Removal of the solvent gave a residue which was distilled through a vigreux column to obtain the title compound, bp 83°-100°/0.25 mm Hg.

1. customIn a dry three-neck flask equipped with a mechanical stirrer and an addition funnel
2. customThe resulting reaction mixture
3. stirringwas stirred for 4 hours
4. filtrationthe mixture was filtered through a dry silica gel column
5. customto obtain a colorless solution
6. customRemoval of the solvent
7. customgave a residue which
8. distillationwas distilled through a vigreux column