HCID 20250618, compound → HCID 20250623, compound

Participants

Reaction Conditions

Reaction Steps

5 g of 2-azidomethylthioxanthone are dissolved in 50 ml of N,N-dimethylformamide, and 0.5 g of Pd-on-charcoal is added, in an autoclave. Hydrogen is then passed in. The reaction is monitored by means of IR spectroscopy. It has ended when the band at 2,100 cm-1 has disappeared. The reaction mixture is diluted with N,N-dimethylformamide, heated to 60° C. and filtered, the filtrate is cooled and water is added. The crystals which have precipitated are separated off by filtration and dried. 4.3 g (95.3% of theory) of 2-aminomethylthioxanthone are obtained. Melting point: 134°-136° C.

Provenance & Evidence