HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromotoluene → Ethyl 3-(4-methylphenyl)-2-propenoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromotoluene | HCID 7805 | — |
| Reactant | Ethyl Acrylate | HCID 8821 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | Ethyl 3-(4-methylphenyl)-2-propenoate | HCID 334099 | 14% |
Reaction Steps
The procedure described in Example 26 is repeated, but using 4.28 g (25 mmols) of 4-bromotoluene and 2.99 ml (27.5 mmols) of ethyl acrylate. After a reaction time of 23 hours at 130° C., 0.67 g (3.5 mmols) of ethyl 4-methylcinnamate is obtained, corresponding to a yield of 14% of theory (conversion figure 1400; Pd content 0.01 mol %).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04564479 |
| Source dataset | uspto-grants-1986_01 |
| ORD ID | ord-daca7fbf1e1f423488e75ef085b7103b |
| Source note | uspto-grants-1986_01 |