HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Bromochlorobenzene → 2-Propenoic acid, 3-(4-chlorophenyl)-, ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Bromochlorobenzene | HCID 7806 | — |
| Reactant | Ethyl Acrylate | HCID 8821 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | 2-Propenoic acid, 3-(4-chlorophenyl)-, ethyl ester | HCID 201471 | 72% |
Reaction Steps
The procedure described in Example 26 is repeated, but using 4.79 g (25 mmols) of 4-bromochlorobenzene and 2.99 ml (27.5 mmols) of ethyl acrylate. After a reaction time of 8 hours at 130° C., 3.79 g (18.0 mmols) of ethyl 4-chlorocinnamate are obtained, corresponding to a yield of 72% of theory (conversion figure 7200; Pd content 0.01 mol %).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04564479 |
| Source dataset | uspto-grants-1986_01 |
| ORD ID | ord-9d2e236336e64d17a9d2b3adbf160d6d |
| Source note | uspto-grants-1986_01 |