HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acrylonitrile → 4-Bromocinnamonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acrylonitrile | HCID 7855 | — |
| Reactant | 1-Bromo-4-iodobenzene | HCID 11522 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | 4-Bromocinnamonitrile | HCID 53480 | 76% |
Reaction Steps
The procedure described in Example 47 is repeated, but using 7.07 g (25 mmols) of 4-bromoiodobenzene and 1.83 g (27.5 mmols) of acrylonitrile. After a reaction time of 8 hours at 130° C., 3.95 g (19.0 mmols) of 4-bromocinnamonitrile are obtained, corresponding to a yield of 76% of theory (conversion figure 7600; Pd content 0.01 mol %).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04564479 |
| Source dataset | uspto-grants-1986_01 |
| ORD ID | ord-8ab49296290e4657888114bf4a135ce1 |
| Source note | uspto-grants-1986_01 |