Acetyl chloride → HCID 70456391, compound

Participants

Reaction Steps

A half g of tert-butyl 3(R)-[1(S)-ethoxycarbonyl-5-phthalimidopentyl]amino-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepine-5-acetate is treated with hydrazine in a manner similar to that described in Reference Example 44, and then reacted with acetyl chloride to give tert-butyl 3(R)-[5-acetylamino-1(S)-ethoxycarbonylpentyl]amino-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepine-5-acetate (0.25 g) as a colorless oil.

Provenance & Evidence