反应详情

3-Amino-1-(2-pyridyl)-2-pyrazoline (1.5 g) was added to formic acid (22 ml) at 60° in an atmosphere of nitrogen. The mixture was stirred whilst acetic anhydride (2.3 ml) was added dropwise. The mixture was heated at 100° for 1 hour before being evaporated in vacuo to give 3-formamido-1-(2-pyridyl)-2-pyrazoline which was recrystallised from isopropanol, m.p. 182°-183° (yield 1.17 g).

1. additionwas added dropwise
2. temperatureThe mixture was heated at 100° for 1 hour
3. custombefore being evaporated in vacuo