Sodium methanolate methanol → HCID 54218980, compound

Participants

Reaction Steps

In another flask were placed 40 g of 4-pentylcyclohexyl-p-(3-bromopropyl)phenyl ketone and 200 ml of CH3OH and stirred. Thereafter, a sodium methylate-methanol solution prepared by dissolving 3.5 g of Na in 80 ml of absolute CH3OH was added thereto dropwise, and the resulting solution was refluxed. After 6 hours, the reaction solution was concentrated and then poured into water, after which the separated oil layer was extracted with benzene. After the benzene was distilled off, the residue was distilled under reduced pressure to obtain 4-pentylcyclohexyl-p-(3-methoxypropyl)phenyl ketone. The boiling point of this compound was 168°-171° C./0.08 mmHg.

Provenance & Evidence