HCID 15597266, compound → HCID 20249852, compound

HRID 1285118Notes

Reaction equation

HRID 1285118 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:9](=[C:10]([O:12][CH3:13])[CH:11]=1)[N:8]([CH3:14])[C:7](=[CH2:15])[C:6]2([CH3:17])[CH3:16].COC1C=C2C(=CC=1)N(CCCCCC)C1(C=[CH:38][C:37]3[CH:40]=[C:41]([N+:46]([O-:48])=[O:47])[CH:42]=[C:43]([O:44][CH3:45])[C:36]=3[S:35]1)C2(C)C>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:9](=[C:10]([O:12][CH3:13])[CH:11]=1)[N:8]([CH3:14])[C:7]1([CH:15]=[CH:38][C:37]3[CH:40]=[C:41]([N+:46]([O-:48])=[O:47])[CH:42]=[C:43]([O:44][CH3:45])[C:36]=3[S:35]1)[C:6]2([CH3:17])[CH3:16]

Participants

3

Reactant 2

HCID 15597266HCID 15597266, compoundHCID 15653903HCID 15653903, compound

Product 1

HCID 20249852HCID 20249852, compoundYield 147%

Procedure

3.4 g of the indoline and 3.2 g of the 3-methoxy-5-nitrosalicylaldehyde obtained in Example 2 were reacted in the same manner as in Example 2 to obtain 4.3 g of intended 5',7'-dimethoxy-1',3',3'-trimethyl-6-nitro-8-methoxyspiro[2H-1-benzothiopyran-2,2'-indoline] (yield 69%, melting point 131° C.).

Sources & evidence

ORD record
ord-4a9373a80f184121af5f5e20d77122e2
Source dataset
uspto-grants-1986_01
Patent number
US04565779

Reaction notes

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