HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-bromobutanimide → 8-(Bromomethyl)-7-chloroquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 7-Chloro-8-methylquinoline | HCID 13090783 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 8-(Bromomethyl)-7-chloroquinoline | HCID 13152196 | — |
Reaction Steps
7-Chloro-8-methylquinoline (1 g.) [Bradford et al., J. Chem. Soc., p. 437 (1947)] is dissolved in 20 ml. of benzene and brominated with one equivalent of N-bromosuccinimide in the presence of catalytic amounts of peroxide. The product, 7-chloro-8-(bromomethyl)quinoline is isolated by evaporation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04565820 |
| Source dataset | uspto-grants-1986_01 |
| ORD ID | ord-eb46dfe8df1d49458b1c024d31e36c74 |
| Source note | uspto-grants-1986_01 |