HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Acetic Anhydride → Chinoin 170
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Acetic Anhydride | HCID 7918 | — |
| Edukt | 2-(Theophyllin-7-yl)-acetamidoxime | HCID 3057490 | — |
| Lösungsmittel | Acetic Acid | HCID 176 | — |
| Produkt | Chinoin 170 | HCID 139570 | 91% |
Reaktionsschritte
15.12 g of 2-(theophyllin-7-yl)-acetamidoxime are heated on water bath for two hours with a mixture of 120 cm3 acetic acid and 8 cm3 of acetic anhydride. The solvent is distilled off and 16.06 g. (91%) of 7-[(5-methyl-1,2,4-oxadiazol-3-yl)-methyl]-theophylline are obtained. M.p.: 135° C. (methanol).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04565817 |
| Quelldatensatz | uspto-grants-1986_01 |
| ORD ID | ord-62e428e27c3148ecb744d87231d5de80 |
| Quellennotiz | uspto-grants-1986_01 |