HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Iodide → 5-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)pentanenitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | Sodium Cyanide | HCID 8929 | — |
| Reactant | HCID 20249931 | HCID 20249931 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 5-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)pentanenitrile | HCID 20249954 | 73% |
Reaction Steps
2.7 g. of theophylline-chloro-butane according to Example b., 0.51 g. of sodium cyanide, 0.01 g. of sodium iodide and 10 cm3 of dimethylformamide are heated at 95° C. for 5 hours. Thus 1.9 g. (73% yield) of δ-(theophylline-7- yl)-valeronitrile are obtained, m.p.: 118°-120° C. (ethylacetate).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04565817 |
| Source dataset | uspto-grants-1986_01 |
| ORD ID | ord-1477b7255cb14dcc9565d8da088d1ba9 |
| Source note | uspto-grants-1986_01 |