HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Cyanide → 6-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)hexanenitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Cyanide | HCID 9032 | — |
| Reactant | 7-(5-Chloropentyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione | HCID 20249955 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 6-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)hexanenitrile | HCID 20249997 | 76.5% |
Reaction Steps
10.0 g. of 1-chloro-5-(theophyllin-7-yl)-pentane, 2.44 g. of potassium cyanide and 40 cm3 of dimethylformamide are reacted according to Example 13c and 7.92 g. (76.5% yield) of 7-(5-cyano-pentan-1-yl)-theophylline are obtained, m.p.: 86°-88° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04565817 |
| Source dataset | uspto-grants-1986_01 |
| ORD ID | ord-292269375d1649688e71da6ec8c96331 |
| Source note | uspto-grants-1986_01 |