HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 2-Bromo-3,4,5,6-tetrafluorobenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-Bromo-3,4,5,6-tetrafluorobenzoic acid | HCID 17750845 | — |
| Product | 2-Bromo-3,4,5,6-tetrafluorobenzoyl chloride | HCID 2783243 | — |
Reaction Steps
365 g (1.33 mol) of 2-bromo-3,4,5,6-tetrafluorobenzoic acid [Tetrahedron 2.3, 4719 (1967)] are introduced into 2 l of thionyl chloride and the mixture is heated under reflux for 11 hours until the evolution of gas stops. Excess thionyl chloride is stripped off in vacuo and the residue is distilled.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05464796 |
| Source dataset | uspto-grants-1995_11 |
| ORD ID | ord-632e860dbe884737aa3786689e299c3d |
| Source note | uspto-grants-1995_11 |