m-Chloroperbenzoic acid → HCID 178510664, compound

Participants

Reaction Steps

To a stirred suspension of N-(5-cyano-1H-imidazol-4-yl)-4-pyridinecarboxamide (0.53 g, 0.0025 mole), which can be made by the procedure of Example 1 substituting isonicotinoyl chloride for the 3-fluorobenzoyl chloride, in 20 ml of ethyl acetate was added 3-chloroperbenzoic acid (0.65 g, 0.003 mole). The mixture was heated at reflux for 15 hours, cooled and the solid product collected by filtration. The solid was washed with ethyl acetate and dried under reduced pressure to give N-(5-cyano-1H-imidazol-4-yl)-4-pyridinecarboxamide N-oxide (0.52 g; mp, 290°).

Provenance & Evidence